well i did say "you could". ive seen quite an improvement on high millage 5sfes(especially highways milles ones), mostly because of sludge buildup. but then id spend money on that before wasting it on headers which wont do anything but reduce back pressure and take some of your low end power. a good tune up will also improve engine life...i doubt headers would. i have serious doubts your not gonna get + MPGs from headers, or at least not enough to jsutify the cost. but you could install a high flow cat and that would likely help alot more since its the most restrictive part of the 5sfe's exhaust.
but hey its your money/time.