I have finished the front door speakers installation. Pretty easy
especially, prying out the door handle bezels, (1-2-3 then done)
hclee25 is right. For any aftermarket 6.5" speaker, you have to drill holes. The three crew holes are not placed evenly 60 degree each

, so I couldn't use the Alpine adapters directly. And the speaker hole in gen'4 Camry front door is too big for 6.5" speaker, you better have adapters with speakers.
To install the door panel back smoothly, you better have the door window glass down.