If I was going with a Double Din unit I would be all over the Eclpise AVN-5495. I'm going with a custom 10.4" Screen in the CD player area myself, but if i wasn't doing that, I'd be saving my pennies for the Eclipse.
One thing though, the dashkit that is coming out from Scosche and Metra, I'm pretty sure those are going to be single DIN. So if you want to go double din it is probably going to have to be custom.
Not sure if you want to go this route, but what I have planned for myself is installing a Xenarc 10.4" Monitor in the space where the CD player is. It should be easier than making a trim kit for a double din.
Then you can do a custom Carputer
Here's my planned setup
I'll also be using a Pioneer DEH-P860MP headunit as well.
Back to the original ? though, check out the Seas Lotus Reference
http://www.mobilesq.com/products/get_product.php?id=1
http://www.seas.no/Lotus/default.htm
For my system I'll be using Peerless XLS 8" Midbass/sub in the doors(there's plenty of room for it)
That's a DLS Iridium 6.5" Mid, there is plenty of room for an 8" if you like alot of midbass.
For the midrange and tweeter I'll be usingthe Seas Excel 5" midrange and I think I've decided to go with LCY 130 Ribbons.
Some other options to consider that will definitely be awesome is the DLS Iridium 8.3 Component system
http://www.dls.se/english/speakers/Iridium83.htm
A Dynaudio Sytem would be awesome.
Morel would be another name to go with.
It all really depends on how and what kind of install you are going with. If you want to use just a 2 way component set using the stock locations, you'd want to use a 7" mid as opposed to an 8" to get better midrange response. And if you are going to be using the tweeter in the stock location you'd want a tweeter that works well off-axis.
There's so many good choices out there, you need to evaluate what kind of installation you want to do, then go into researching different components to see how they work in different situations.
Check out these forums
www.elitecaraudio.com and
www.diymobilaudio.com