I was able to install
this car seat in the middle facing backwards and now facing forward in my 2010 highlander using the two safety latches closes to the center. Now that the seat is facing forward, I thread the top harness through the center headrest and over to the driver side rear latch behind the rear seat. Everything seems secure to me. This car seat might be a little too big for a newborn though. Before having the highlander, we had the
Chicco Keyfit in another vehicle. I haven't tried in the highlander but the locking latches on the booster portion might be a bit short to fit in the center. Using the center seat belt might be an option but I'd recommend only using the latches. You can really pull the straps tight and the booster will not move. I don't think you can get it as tight/secure using only the seat belts.