Had an '02 HL Limited with over 120,000 trouble free miles (just tires/brakes, nothing more). It was my 'everything' vehicle - commuting 50 miles/day, vacation trips, etc. so it was not 'babied' by any means. Got the 'bug' to buy a new car and went with a Subaru OB, based somewhat on Motor Trend's "SUV of the Year" award. After 9 months and 9,000 miles, 4 trips to the dealership and 2-3 weeks in a loaner I got rid of it and am now driving an '11 HL Limited.
My only regrets in all of this:
1) Should have kept the '02, I'd probably still be driving it today with about 150,000 miles on it (but I really have to admit the '11 is a lot nicer),
2) Buying the Subaru - it was the most problematic, frustrating vehicle I've ever owned in nearly 40 years of buying new cars, and that was after just 9 months of ownership. I can't imagine how I'd feel if I had kept it for 100K miles.
My only 2 complaints about the '11 are some small rattles behind the dash - particularly when it's cold out. This isn't unique to the '11 though as my '02 did the same thing - must be a 'design feature'

. The second is all current Highlanders come with the third row seat that I have no use for - would have bought one without it if they were available, but that's life.