I have used synthetics in vehicles starting at about 6,000 miles and up to nearly 200,000 miles and it never created a problem.
I have driven many vehicles past 200,000 miles using synthetic oil and have never had a problem with oil leaks or seals "drying up". The rear main seal on my '95 Formula is original and the car has over 242,000 miles on it using Mobil 1 with 3,000 mile service intervals. I use Mobil 1 in my '06 Camry with 5,000 mile service intervals.
My Parents have an '05 Highlander that they use Mobil 1 in (started synthetic at 5,000 miles I believe) and a '97 Oldsmobile they started using Mobil 1 in at about 104,000 miles. Now it has about 125,000 miles on it. Neither vehicle has any problems either. The Olds leaked oil before the synthetic and still does now. It doesn't leak enough to go down on the stick.
If it's not a financial burden, I would (and do) use synthetic oil. It is more stable, and does offer better protection. You may not need the extra protection, but it's good to have.
Here's a pic of the engine on my '95 Formula left cylinder head. At this time the engine had 221,000 miles on it. I've never seen a conventional oil keep the inside of an engine this clean. NEVER. I've seen thousands of engines that have used conventional oil look terrible with half the miles on them.