Well, to get the full benefits of the fluid upgrade, you want a full change.
I actually do the flush every 30k, disconnecting the return hose from the cooler in the rad. But I don't bother to drop the pan. As noted elsewhere, the "filter" is like a screen.
Figure on using 12 - 13 quarts for the flush. If you don't have a second car around, have 16 qts on hand when you start, because Mr. Murphy was a bloody optimist.
Use a clear tube (Lowes, HD) to make it easier to track the fluid color change to new looking.