The question you should be asking isn't "would my ECU get messed up" it's "would my ECU mess up my car". When you start making changes to the way the engine breathes it starts drifting outside the parameters the ECU is programmed to operate under.
The worst case is a lean condition that could damage the motor. In reality with those mods you probably just wouldn't be taking full advantage of your mods without some sort of engine management.
It is highly recommended that you read
http://www.mrcontrols.com/index.html before you start adding power.