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I have 245/40-18's on mine -- Goodyear Eagle F1's. I didn't notice any rubbing until I installed the TRD springs. Now I do have a slight (and I emphasize slight) rubbing issue on the driver's side front when I make a complete turn of the wheel to the left (making a left-hand U turn). The rub removed some of the undercoating inside my wheel well. However, I just applied new undercoating and don't turn the wheel completely to the left. I love the look and handling of the 245's but if there is any dips or grooves in the road, these tires pull hard in the direction of the grooves/dips. As a result, I will most likely put 235's or 225's on it when I need new tires.
I hope this helps.
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07 SE V6, blue ribbon, 3M clear bra, GS430 chrome rims, 245/40-18 Goodyear Eagle F1 AS, 35% tint, Eagle Eyes LED tail lights, TRD springs, all interior lights LEDs, Camry door sills, chrome trunk piece, chrome door handles (Chrome Masters), and TRD emblem. 
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