The flashing O/D light means you have a problem code stored concerning the transmission. It's probably the speed sensors but I'd put it in diagnostic mode and pull the code to be sure.
Also, make sure yer battery is up to snuff as it can cause other sensors to indicate failures because of the low voltage.
You'll need to pull the diagnostic code fer the ABS...

If the speed sensor circuit isn't functioning...it could be the cause fer both systems to not function properly.
Are yer back brakes locking up? Are you sure the LSPV (load sensing proportional valve) is working correctly? Block the front wheels and jack up the rear by the differential. Release the parking brake and spin the rear wheels. Step on the brake. Are the rear wheels stopping?