Very similar, if not identical.
You need an 2 channel amplifier. which needs power, ground, and remote turn on wires, along side with line level RCA from the radios preamp outputs. Make sure the RCA outs are labeled front or rear.
Wire the 6x9s to the amplifier, pretty straightforward.
After the system is operational be sure to set gains/line levels to avoid distorting and blowing up your speakers.
If you've done a subwoofer installation than this should be no problem. The only difference is the speakers, and the signal being fed to the amplifier.