Personally, I like the generation 3 4 cylinder 5SFE engine. It's not uncommon for these engines to go 200,000 miles or more with very few problems. They are also easier to work on yourself than the V 6's. If your are going to be hauling a lot of weight or pulling a trailer more than 1000 pounds, then the V 6 might be a better choice for you. YMMV.
Mike
Mike