This should answer all your questions.
I didn’t find the wiki article to be particularly clear about what drivetrain was offered in the US with the 2007 Hybrid model. But I posted this same question to the Toyota sub on Reddit and a user there pointed me to the 2007 Highlander brochure. And that definitively answered my question. The short version is that both 2WD & 4WD 2007 Highlander Hybrid we’re available in the US.This should answer all your questions.