Synthetic oils, with all of their detergents, actually do the most "harm" to the engine between 0-3,000 miles. The oil is at its peak protection level from 3,000-7,500 miles, and then after it's still good until over 10,000 miles. 10,000 mile oil changes, while new to Toyota, are not new to the automotive world. The Germans have been running them for over a decade and their intervals often exceed 10,000 miles. Run a Used Oil Analysis if you really want to be sure just how good these oils are and you'll see that 10,000 is more than adequate for intervals.